Forxiga (Dapagliflozin) 10mg x 50Tabs
Do SGLT2 Inhibitors (Fosiga) Have a Weight Loss Effect? ??
Have you ever heard of a drug called SGLT2 inhibitor (Fosiga)?
If you are interested in dieting, you may have heard of it.
These drugs are treatments for type 2 diabetes. It has also been reported that oral administration has a weight-loss effect due to the mechanism of treatment for patients with type 2 diabetes.
Many people may be interested in the weight loss effect, but I will explain in detail about the SGLT2 inhibitor (Fosiga).
What kind of drug is SGLT2 inhibitor (Fosiga)? What is different from other medicines?
SGLT2 inhibitors are drugs that have been researched and developed as therapeutic agents for type 2 diabetes. It is also indicated as a treatment for type 2 diabetes in medical insurance.
SGLT2 is a protein in the kidney that has the effect of preventing sugar from escaping into the urine, but SGLT2 inhibitors such as Fossiga suppress the effect of SGLT2 from the blood. This is because it has the function of promoting the excretion of sugar into the urine (inhibiting reabsorption).
In other words, SGLT2 inhibitors have the effect of leaving the sugar (glucose) ingested from the diet in the urine and excreting it from the body.
This effect itself is present in everyone, so even if you do not have type 2 diabetes, sugar will be excreted from your urine. As a result, taking SGLT2 inhibitors can help you lose weight. Since the amount actually excreted is about 200 kcal per day (1 to 1.5 rice balls), there is logically an excretion effect of about 6000 kcal per month. Generally, a weight loss effect of about 2-3 kg has been reported in the paper.
Also recently, a press release was issued on October 10, 2020 from AstraZeneca’s UK headquarters stating that Fossiga, one of the SGLT2 inhibitors, was indicated not only for type 2 diabetes but also for chronic heart failure. I did. On November 27, 2020, the Ministry of Health, Labor and Welfare approved additional indications for chronic heart failure in Japan.
Other drugs, such as GLP-1 inhibitors and appetite suppressants, work on the brain to suppress appetite and reduce the amount of food by feeling full, but SGLT2 inhibitors have a weight loss effect. By excreting sugar from the urine, the weight loss effect can be obtained.
How to take SGLT2 inhibitors?
The SGLT2 inhibitor Fossiga is very easy to take, just take one tablet once a day. It is not affected by the amount of food you eat, so it is a good idea to decide your own time to drink so that you do not forget to take it.
What are the side effects of SGLT2 inhibitors (Fosiga)?
So what are the side effects?
First of all, sugar is excreted in the urine, and at the same time, the water in the body is also excreted as urine. This can lead to increased urine output and frequent urination, or frequent urination that produces a lot of urine, which can lead to dry throat.
In addition, sugar is contained in places where urine does not originally contain sugar, but sugar also serves as food for pathogens such as bacteria, so it is also a side effect that it is easy to get urinary tract infections. Can be mentioned. Especially for women, you need to be careful about urinary tract infections