Methyltrienolone 500mcg x 100tabs(EVOLIX)
Effective Dose (Men): 500-2000 mcg/day
Effective Dose (Women): Not Recommended
Half-Life: 24-48 Hours
Detection Time: ６month+
Anabolic/Androgenic Ratio: 12,000+/6,000+
Metribolone, also called methyltrienolone, is a potent oral anabolic steroid that was originally developed in the 1960’s to treat advanced breast cancer. However, it was quickly pulled from the market because of its harsh side effects on the body, especially the liver. Therefore, today it is used in research only.
Just like with most steroids, bodybuilders and athletes have experimented with this steroid since then, but due to its harshness and rarity, it’s not popular at all.
Table of Contents
3 Comparisons to oral trenbolone
4 Side Effects
Metribolone is best known for being the steroid that caused 11 members of the Greek weightlifting team, and 4 members of their track and field team, to test positive ahead of the 2008 Beijing Olympic Games. As a result, their weightlifting coach, Christos Lakovou, was suspended for his role in the scandal.
Perhaps, the only good news is that metribolone does not aromatize or convert into estrogen. Yet, it is extremely hepatotoxic, and it could be comparable to stacking 2 or 3 of the harshest oral steroids at the same time. In fact, studies have shown that the experimental rats developed organ cancer when given this steroid at abusive levels. Obviously, we can presume that this steroid has a 17-alpha methyl group attachment, which will lead to tremendous strain on the liver.
Furthermore, metribolone is also a 19nor steroid (just like trenbolone or deca durabolin), and it has the ability to bind equally well in all tissues. Hence, it is a great choice in universities studying androgen receptors. As a matter of fact, it has been used since the 70’s for research in animals because it is so resistant to metabolism, meaning it doesn’t interfere with experimental results. Interestingly, clinical research on humans is no longer an option due to its dangers.
Comparisons to oral trenbolone
A lot of people on forums will compare metribolone to oral trenbolone, and online steroid ‘gurus’ will claim that metribolone is the “most powerful steroid ever.” Are they right?
YES but it‘s makes liver problem
As mentioned, metribolone does not aromatize into estrogen, but this can be a tricky issue. For instance, Anadrol is another oral steroid that does not aromatize, but it still binds with estrogen. In the meantime, metribolone will bind to progesterone receptors, as it is a progestin 19nor compound. Thus, even though there is no aromatization to estrogen, you can still end up with progestin based gynecomastia (bitch tits) anyway.
Additionally, due to its strength, metribolone causes such androgenic sides as aggression, acne, and male pattern baldness. If that weren’t enough, there are also the common steroid related issues, which are heart strain and suppression.
For women it will cause pronounced virilization symptoms, so female athletes should avoid metribolone at all cost.
Finally, liver damage can easily occur with metribolone, not just because it is 17-aa, but because it is highly resistant to hepatic metabolism. Consequently, if you choose to run this compound, you need a good liver supporting supplement, and you should get blood work done both during and after usage. Remember, it is easily the most liver toxic steroid in existence! Therefore, a strong support supplement is crucial, and I recommend using a triple dosage of Silymarin or URSO.
Those who want to try it will run 0.5 milligrams (mgs) to 4mgs per day split dose. Regarding the cycle duration, you should not exceed 3 to 4 weeks of use.
Metribolone has a half-life of about 4-6 hours, which is a short time, and additionally has a heavy burden on the liver
Although there is a negative point, EVOLIX has developed an evolutionary formulation of Metribolone.
Orally administered drugs migrate first into the liver when they are absorbed from the intestine, they are metabolized and then transferred into the blood.
The first pass effect is that medication absorbed in this manner first passes through the liver and undergoes metabolism.
For drugs that are liable to be metabolized by the liver, most of them are decomposed by the first pass effect.
For this reason, it is necessary to consider the first-pass effect at the time of drug development, and many oral steroid agents have methyl group
Although it does not get metabolized by adding it, it brings out the medicinal effect, but it leads to the result of putting a big burden on the liver.
There is injection medicine as a method not affecting the first pass effect depending on the administration method of medicine which does not have to consider absorption from intestine.
A formulation with a methyl group added to the alpha 17 position can be a stress to the liver even if ingested as an injection, but by reducing the burden than oral administration and fully demonstrating the medicinal effect, the half life is extended Methyltrienolone Depot is the formulation possible with one injection per day.